Glycomics & Glycoproteomics: From Analytics to Function
نویسندگان
چکیده
منابع مشابه
Glycomics and Glycoproteomics Databases in Japan and Asia
The ‘‘Integrated Database Project’’ was initiated to establish a publically accessible database to integrate all useful life science databases in Japan. Our JCGGDB (Japan Consortium for Glycobiology and Glycotechnology Database) was selected as a promotion program in the project, focussing on the integration of all the glycan-related databases and establishment of user-friendly search systems. ...
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Glycans stand out from all classes of biomolecules because of their unsurpassed structural complexity. This is generated by variability in anomeric status of the glycosidic bond and its linkage points, ring size, potential for branching and introduction of diverse site-specific substitutions. What poses an enormous challenge for analytical processing is, at the same time, the basis for the fing...
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Chemical glycomics uses synthetic chemistry to procure defined carbohydrate molecules to study the glycans involved in many functions in the living cell. Based on an automated synthesis platform, a host of synthetic tools including carbohydrate microarrays has been developed. These tools have been employed to dissect carbohydrate-copolymer interactions. Basic research in the glycomics arena is ...
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Glycans, or complex carbohydrates, are a ubiquitous class of biological molecule which impinge on a variety of physiological processes ranging from signal transduction to tissue development and microbial pathogenesis. In comparison to DNA and proteins, glycans present unique challenges to the study of their structure and function owing to their complex and heterogeneous structures and the domin...
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ژورنال
عنوان ژورنال: Molecular Omics
سال: 2021
ISSN: 2515-4184
DOI: 10.1039/d0mo90019b